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Degradation of endogenous hepatic heme by pathways not yielding carbon monoxide. Studies in normal rat liver and in primary hepatocyte culture.

The conversion of endogenous hepatic heme to bilirubin and CO is established. However, it is unknown whether this process is quantitative or whether heme may be degraded to other products as well. To study this question, we administered the heme precursor, delta-amino-[5-14C]levulinic acid to rats i...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Bissell, D M, Guzelian, P S
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1980
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371446/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7364941/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109767
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