Pramipexole in patients with early Parkinson's disease (PROUD): a randomised delayed-start trial

BACKGROUND: In models of dopaminergic neuronal loss, the dopamine agonist pramipexole has exhibited neuroprotective properties. The Pramipexole On Underlying Disease (PROUD) study was designed to identify whether early versus delayed pramipexole initiation has clinical and neuroimaging benefits in p...

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Autors principals: Schapira, Anthony HV, McDermott, Michael P, Barone, Paolo, Comella, Cynthia L, Albrecht, Stefan, Hsu, Helen H, Massey, Daniel H, Mizuno, Yoshikuni, Poewe, Werner, Rascol, Olivier, Marek, Kenneth
Format: Artigo
Idioma:Inglês
Publicat: Lancet Pub. Group 2013
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3714436/
https://ncbi.nlm.nih.gov/pubmed/23726851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1474-4422(13)70117-0
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