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In vitro idiotypic suppression of chronic lymphocytic leukemia lymphocytes secreting monoclonal immunoglobulin M anti-sheep erythrocyte antibody.

A patient with chronic lymphocytic leukemia was found to have B cells with surface immunoglobulin (Ig)M manifesting anti-sheep erythrocyte (SRBC) specificity together with a high titer serum monoclonal anti-SRBC IgM antibody. By immunizing a sheep with the monoclonal IgM antibody, followed by multip...

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Pubblicato in:J Clin Invest
Autori principali: Bona, C A, Fauci, A S
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1980
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371420/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6986413/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109724
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