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Asynchronous Onset of Clinical Disease in BSE-Infected Macaques

To estimate the effect of the variability of prion disease onset on primary bovine spongiform encephalopathy transmission to humans, we studied 6 cynomolgus macaques. The preclinical incubation period was significantly prolonged in 2 animals, implying that onset of variant Creutzfeldt-Jacob disease...

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Bibliografiske detaljer
Main Authors: Montag, Judith, Schulz-Schaeffer, Walter, Schrod, Annette, Hunsmann, Gerhard, Motzkus, Dirk
Format: Artigo
Sprog:Inglês
Udgivet: Centers for Disease Control and Prevention 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3713963/
https://ncbi.nlm.nih.gov/pubmed/23764183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3201/eid1907.120438
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