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Total syntheses of the squalene-derived halogenated polyethers ent-dioxepandehydrothyrsiferol and armatol A via bromonium- and Lewis acid-initiated epoxide-opening cascades

Herein we describe in full our investigations leading to the first total syntheses of ent-dioxepandehydrothyrsiferol and armatol A. Discovery of a bromonium-initiated epoxide-opening cascade enabled novel tactics for constructing key fragments found in both natural products and have led us to revise...

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Hlavní autoři: Underwood, Brian S., Tanuwidjaja, Jessica, Ng, Sze-Sze, Jamison, Timothy F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3713853/
https://ncbi.nlm.nih.gov/pubmed/23878408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2013.04.041
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