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Redox-Based Control of the Transformation and Activation of siRNA Complexes in Extracellular Environments Using Ferrocenyl Lipids
We report physical characterization and biological evaluation of complexes of siRNA formed using a cationic lipid (BFDMA) containing redox-active ferrocenyl groups at the end of each hydrophobic tail. We demonstrate that control over the redox state of BFDMA can be used to influence key physical pro...
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| Asıl Yazarlar: | , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2013
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3713503/ https://ncbi.nlm.nih.gov/pubmed/23701636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja403546b |
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