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Redox-Based Control of the Transformation and Activation of siRNA Complexes in Extracellular Environments Using Ferrocenyl Lipids

We report physical characterization and biological evaluation of complexes of siRNA formed using a cationic lipid (BFDMA) containing redox-active ferrocenyl groups at the end of each hydrophobic tail. We demonstrate that control over the redox state of BFDMA can be used to influence key physical pro...

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Detalhes bibliográficos
Main Authors: Aytar, Burcu S., Muller, John P. E., Kondo, Yukishige, Talmon, Yeshayahu, Abbott, Nicholas L., Lynn, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3713503/
https://ncbi.nlm.nih.gov/pubmed/23701636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja403546b
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