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EZH2 promotes E2F driven SCLC tumorigenesis through modulation of apoptosis and cell cycle regulation

INTRODUCTION: While EZH2 has been associated with both non small cell and small cell lung cancers, current observations suggest different mechanisms of EZH2 activation and overexpression in these lung cancer types. Globally, small cell lung cancer (SCLC) kills 200,000 people yearly. New clinical app...

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Detalhes bibliográficos
Main Authors: Hubaux, Roland, Thu, Kelsie L., Coe, Bradley P., MacAulay, Calum, Lam, Stephen, Lam, Wan L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3713495/
https://ncbi.nlm.nih.gov/pubmed/23857401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0b013e318298762f
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