Antiretroviral Therapy Corrects HIV-1 Induced Expansion of CD8(+) CD45RA(+) CD27(−) CD11a(bright) Activated T cells

BACKGROUND: HIV-infection decreases thymic output and induces chronic T cell activation. OBJECTIVE: Extended immune phenotyping of CD4(+) and CD8(+) T cells subsets were combined with TREC levels and measures of TCR repertoire perturbations in CD8(+) T cell subpopulation in order to define the globa...

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Main Authors: Yin, Li, Rodriguez, Carina A, Hou, Wei, Potter, Olivia, Caplan, Margaret J., Goodenow, Maureen M., Sleasman, John W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3713492/
https://ncbi.nlm.nih.gov/pubmed/18538835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2008.04.029
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