ATR acts stage specifically to regulate multiple aspects of mammalian meiotic silencing

In mammals, homologs that fail to synapse during meiosis are transcriptionally inactivated. This process, meiotic silencing, drives inactivation of the heterologous XY bivalent in male germ cells (meiotic sex chromosome inactivation [MSCI]) and is thought to act as a meiotic surveillance mechanism....

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Detalhes bibliográficos
Main Authors: Royo, Hélène, Prosser, Haydn, Ruzankina, Yaroslava, Mahadevaiah, Shantha K., Cloutier, Jeffrey M., Baumann, Marek, Fukuda, Tomoyuki, Höög, Christer, Tóth, Attila, de Rooij, Dirk G., Bradley, Allan, Brown, Eric J., Turner, James M.A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2013
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3713429/
https://ncbi.nlm.nih.gov/pubmed/23824539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.219477.113
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