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Structural and energetic properties of canonical and oxidized telomeric complexes studied by molecular dynamics simulations

The structural and energetic properties of native and oxidized telomeric complexes were defined by means of molecular dynamic (MD) simulations. As a starting point, the experimental conformation of B-DNA d(GpTpTpApGpGpGpTpTpApGpGpG) oligomer bound to human protein telomeric repeat binding factor 1 (...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Czeleń, Przemysław, Cysewski, Piotr
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Berlin Heidelberg 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3713266/
https://ncbi.nlm.nih.gov/pubmed/23674370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00894-013-1859-z
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