Cardiac-Specific Overexpression of CYP2J2 Attenuates Diabetic Cardiomyopathy in Male Streptozotocin-Induced Diabetic Mice

Cytochrome P450 (CYP) epoxygenases metabolize arachidonic acid to biologically active cis-epoxyeicosatrienoic acids, which have potent vasodilatory, antiinflammatory, antiapoptotic, and antidiabetes properties. Here, we showed the effects of cardiac-specific overexpression of CYP epoxygenase 2J2 (CY...

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Detalhes bibliográficos
Main Authors: Ma, Ben, Xiong, Xiaojv, Chen, Chen, Li, Huaping, Xu, Xizhen, Li, Xuguang, Li, Rui, Chen, Guangzhi, Dackor, Ryan T., Zeldin, Darryl C., Wang, Dao Wen
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2013
Assuntos:
Renal-Cardiac-Vascular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3713213/
https://ncbi.nlm.nih.gov/pubmed/23696562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-2166
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