Redundancy in Kiss1 Expression Safeguards Reproduction in the Mouse

Kisspeptin (Kiss1) signaling to GnRH neurons is widely acknowledged to be a prerequisite for puberty and reproduction. Animals lacking functional genes for either kisspeptin or its receptor exhibit low gonadotropin secretion and infertility. Paradoxically, a recent study reported that genetic ablati...

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Detalles Bibliográficos
Autores principales: Popa, Simina M., Moriyama, Ryutaro M., Caligioni, Claudia S., Yang, Jasmine J., Cho, Caroline M., Concepcion, Tessa L., Oakley, Amy E., Lee, In Hae, Sanz, Elisenda, Amieux, Paul S., Caraty, Alain, Palmiter, Richard D., Navarro, Victor M., Chan, Yee-Ming, Seminara, Stephanie B., Clifton, Donald K., Steiner, Robert A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Endocrine Society 2013
Materias:
Neuroendocrinology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3713212/
https://ncbi.nlm.nih.gov/pubmed/23736293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2013-1222
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