Alteration of Mitochondrial Function and Insulin Sensitivity in Primary Mouse Skeletal Muscle Cells Isolated From Transgenic and Knockout Mice: Role of OGG1

Recent evidence has linked mitochondrial dysfunction and DNA damage, increased oxidative stress in skeletal muscle, and insulin resistance (IR). The purpose of this study was to determine the role of the DNA repair enzyme, human 8-oxoguanine DNA glycosylase/apurinic/apyrimidinic lyase (hOGG1), on pa...

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Detalhes bibliográficos
Main Authors: Yuzefovych, Larysa V., Schuler, A. Michele, Chen, Jemimah, Alvarez, Diego F., Eide, Lars, LeDoux, Susan P., Wilson, Glenn L., Rachek, Lyudmila I.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2013
Assuntos:
Diabetes-Insulin-Glucagon-Gastrointestinal
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3713209/
https://ncbi.nlm.nih.gov/pubmed/23748360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2013-1076
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