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Neisseria gonorrhoeae Phagosomes Delay Fusion with Primary Granules to Enhance Bacterial Survival Inside Human Neutrophils

Symptomatic infection with Neisseria gonorrhoeae (Gc) promotes inflammation driven by polymorphonuclear leukocytes (PMNs, neutrophils), yet some Gc survive PMN exposure during infection. Here we report a novel mechanism of gonococcal resistance to PMNs: Gc phagosomes avoid maturation into phagolysos...

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Detalhes bibliográficos
Main Authors: Johnson, M. Brittany, Criss, Alison K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3713093/
https://ncbi.nlm.nih.gov/pubmed/23374609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cmi.12117
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