Targeting mTOR to Overcome Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Resistance in Non-Small Cell Lung Cancer Cells

AIMS: Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) have shown dramatic clinical benefits in advanced non-small cell lung cancer (NSCLC); however, resistance remains a serious problem in clinical practice. The present study analyzed mTOR-associated signaling-pathway diffe...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Fei, Shi-Jiang, Zhang, Xu-Chao, Dong, Song, Cheng, Hua, Zhang, Yi-Fang, Huang, Ling, Zhou, Hai-Yu, Xie, Zhi, Chen, Zhi-Hong, Wu, Yi-Long
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712950/
https://ncbi.nlm.nih.gov/pubmed/23874880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069104
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