Hepatitis B Virus S Protein Enhances Sperm Apoptosis and Reduces Sperm Fertilizing Capacity In Vitro

OBJECTIVE: Studying the impact of Hepatitis B virus S protein (HBs) on early apoptotic events in human spermatozoa and sperm fertilizing capacity. METHODOLOGY/PRINCIPAL FINDINGS: Spermatozoa were exposed to HBs (0, 25, 50, 100 µg/ml) for 3 h, and then fluo-4 AM calcium assay, Calcein/Co(2+) assay, p...

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Main Authors: Huang, JiHua, Zhong, Ying, Fang, XiaoWu, Xie, QingDong, Kang, XiangJin, Wu, RiRan, Li, FangZheng, Xu, XiaoQin, Lu, Hui, Xu, Lan, Huang, TianHua
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712947/
https://ncbi.nlm.nih.gov/pubmed/23874723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068688
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