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Changes in the Transcriptome of the Human Endometrial Ishikawa Cancer Cell Line Induced by Estrogen, Progesterone, Tamoxifen, and Mifepristone (RU486) as Detected by RNA-Sequencing

BACKGROUND: Estrogen (E2) and progesterone (P4) are key players in the maturation of the human endometrium. The corresponding steroid hormone modulators, tamoxifen (TAM) and mifepristone (RU486) are widely used in breast cancer therapy and for contraception purposes, respectively. METHODOLOGY/PRINCI...

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Main Authors: Tamm-Rosenstein, Karin, Simm, Jaak, Suhorutshenko, Marina, Salumets, Andres, Metsis, Madis
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712916/
https://ncbi.nlm.nih.gov/pubmed/23874806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068907
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