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Prevention and Inhibition of TC-1 Cell Growth in Tumor Bearing Mice by HPV16 E7 Protein in Fusion with Shiga Toxin B-Subunit from shigella dysenteriae

OBJECTIVE: For immunotherapy of human papillomavirus (HPV) -16-associated cervical cancers the E7 protein is considered a prime candidate. However it is a poor inducer of cytotoxic T-cell response, when being used as a singular antigen in protein vaccination. Hence, in this study we focused on the u...

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Autors principals: Sadraeian, Mohammad, Khoshnood Mansoorkhani, Mohammad Javad, Mohkam, Milad, Rasoul-Amini, Sara, Hesaraki, Mahdi, Ghasemi, Younes
Format: Artigo
Idioma:Inglês
Publicat: Royan Institute 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712779/
https://ncbi.nlm.nih.gov/pubmed/23862120
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