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Do Non-Genomically Encoded Fusion Transcripts Cause Recurrent Chromosomal Translocations?

We among others have recently demonstrated that normal cells produce “fusion mRNAs”. These fusion mRNAs do not derive from rearranged genomic loci, but rather they are derived from “early-terminated transcripts” (ETTs). Premature transcriptional termination takes place in intronic sequences that bel...

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Detalhes bibliográficos
Main Authors: Kowarz, Eric, Dingermann, Theo, Marschalek, Rolf
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712730/
https://ncbi.nlm.nih.gov/pubmed/24213499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers4041036
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