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Use of Phage Display to Generate Conformation-Sensor Recombinant Antibodies
We describe a phage display approach that we have previously used to generate conformation-sensor antibodies that recognize specifically and stabilize the oxidized, inactive conformation of protein tyrosine phosphatase 1B (PTP1B). We use a solution-based panning and screening strategy conducted in t...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3712638/ https://ncbi.nlm.nih.gov/pubmed/23154784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2012.132 |
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