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Nuclear magnetic resonance in conjunction with functional genomics suggests mitochondrial dysfunction in a murine model of cancer cachexia

Cancer patients commonly suffer from cachexia, a syndrome in which tumors induce metabolic changes in the host that lead to massive loss in skeletal muscle mass. Using a preclinical mouse model of cancer cachexia, we tested the hypothesis that tumor inoculation causes a reduction in ATP synthesis an...

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Autors principals: CONSTANTINOU, CATERINA, FONTES DE OLIVEIRA, CIBELY CRISTINE, MINTZOPOULOS, DIONYSSIOS, BUSQUETS, SILVIA, HE, JIANXIN, KESARWANI, MEENU, MINDRINOS, MICHAEL, RAHME, LAURENCE G., ARGILÉS, JOSEP M., TZIKA, A. ARIA
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712618/
https://ncbi.nlm.nih.gov/pubmed/21069263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2010.557
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