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Differential epigenome-wide DNA methylation patterns in childhood obesity-associated asthma

While DNA methylation plays a role in T-helper (Th) cell maturation, its potential dysregulation in the non-atopic Th1-polarized systemic inflammation observed in obesity-associated asthma is unknown. We studied DNA methylation epigenome-wide in peripheral blood mononuclear cells (PBMCs) from 8 obes...

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Detalhes bibliográficos
Main Authors: Rastogi, Deepa, Suzuki, Masako, Greally, John M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712321/
https://ncbi.nlm.nih.gov/pubmed/23857381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02164
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