Transforming growth factor-β stimulates the expression of eotaxin/CC chemokine ligand 11 and its promoter activity through binding site for nuclear factor-κB in airway smooth muscle cells

BACKGROUND: Chemokines ligands of CCR3 including eotaxin/CC chemokine ligand 11 (CCL11) may contribute to the pathogenesis of asthma. These chemokines and a growth factor (TGF-β) may be involved in the process of airway remodelling. OBJECTIVE: We analysed the effects of TGF-β on the expression of CC...

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Hauptverfasser: Matsukura, S., Odaka, M., Kurokawa, M., Kuga, H., Homma, T., Takeuchi, H., Notomi, K., Kokubu, F., Kawaguchi, M., Schleimer, R. P., Johnson, M. W., Adachi, M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712283/
https://ncbi.nlm.nih.gov/pubmed/20214667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2222.2010.03474.x
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