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Molecular Dynamics Studies on the Conformational Transitions of Adenylate Kinase: A Computational Evidence for the Conformational Selection Mechanism

Escherichia coli adenylate kinase (ADK) is a monomeric phosphotransferase enzyme that catalyzes reversible transfer of phosphoryl group from ATP to AMP with a large-scale domain motion. The detailed mechanism for this conformational transition remains unknown. In the current study, we performed long...

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Главные авторы: Ping, Jie, Hao, Pei, Li, Yi-Xue, Wang, Jing-Fang
Формат: Artigo
Язык:Inglês
Опубликовано: Hindawi Publishing Corporation 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712241/
https://ncbi.nlm.nih.gov/pubmed/23936827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/628536
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