Receptor for advanced glycation endproducts (RAGE) deficiency protects against MPTP toxicity

Parkinson's disease (PD) is a common neurodegenerative disorder of unknown pathogenesis characterized by the loss of nigrostriatal dopaminergic neurons. Oxidative stress, microglial activation and inflammatory responses seem to contribute to the pathogenesis. The receptor for advanced glycation...

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Detalhes bibliográficos
Main Authors: Teismann, Peter, Sathe, Kinnari, Bierhaus, Angelika, Leng, Lin, Martin, Heather L., Bucala, Richard, Weigle, Bernd, Nawroth, Peter P., Schulz, Jörg B.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2012
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712169/
https://ncbi.nlm.nih.gov/pubmed/22227007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2011.12.006
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