Receptor for advanced glycation endproducts (RAGE) deficiency protects against MPTP toxicity

Parkinson's disease (PD) is a common neurodegenerative disorder of unknown pathogenesis characterized by the loss of nigrostriatal dopaminergic neurons. Oxidative stress, microglial activation and inflammatory responses seem to contribute to the pathogenesis. The receptor for advanced glycation...

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Dades bibliogràfiques
Autors principals: Teismann, Peter, Sathe, Kinnari, Bierhaus, Angelika, Leng, Lin, Martin, Heather L., Bucala, Richard, Weigle, Bernd, Nawroth, Peter P., Schulz, Jörg B.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2012
Matèries:
Regular Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712169/
https://ncbi.nlm.nih.gov/pubmed/22227007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2011.12.006
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