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Condensin and the spindle midzone prevent cytokinesis failure induced by chromatin bridges in C. elegans embryos

BACKGROUND: During cell division, chromosomes must clear the path of the cleavage furrow before the onset of cytokinesis. The abscission checkpoint in mammalian cells stabilizes the cleavage furrow in the presence of a chromatin obstruction. This provides time to resolve the obstruction before the c...

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Autori principali: Bembenek, Joshua N., Verbrugghe, Koen J.C., Khanikar, Jayshree, Csankovszki, Györgyi, Chan, Raymond C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712122/
https://ncbi.nlm.nih.gov/pubmed/23684975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2013.04.028
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