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Peroxiredoxin stabilization of DE-Cadherin promotes primordial germ cell adhesion

Regulated adhesion between cells and their environment is critical for normal cell migration. We have identified mutations in a gene encoding the Drosophila hydrogen peroxide (H(2)O(2))-degrading enzyme Jafrac1, which lead to germ cell adhesion defects. During gastrulation, primordial germ cells (PG...

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Detalhes bibliográficos
Main Authors: DeGennaro, Matthew, Hurd, Thomas Ryan, Siekhaus, Daria Elisabeth, Biteau, Benoit, Jasper, Heinrich, Lehmann, Ruth
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712085/
https://ncbi.nlm.nih.gov/pubmed/21316590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2010.12.007
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