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AMPK: A Target for Drugs and Natural Products With Effects on Both Diabetes and Cancer

The AMP-activated protein kinase (AMPK) is a highly conserved sensor of cellular energy that appears to have arisen at an early stage during eukaryotic evolution. In 2001 it was shown to be activated by metformin, currently the major drug for treatment for type 2 diabetes. Although the known metabol...

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Détails bibliographiques
Auteur principal: Hardie, D. Grahame
Format: Artigo
Langue:Inglês
Publié: American Diabetes Association 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712072/
https://ncbi.nlm.nih.gov/pubmed/23801715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-0368
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