Mechanisms Underlying the Onset of Oral Lipid–Induced Skeletal Muscle Insulin Resistance in Humans

Several mechanisms, such as innate immune responses via Toll-like receptor-4, accumulation of diacylglycerols (DAG)/ceramides, and activation of protein kinase C (PKC), are considered to underlie skeletal muscle insulin resistance. In this study, we examined initial events occurring during the onset...

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Main Authors: Nowotny, Bettina, Zahiragic, Lejla, Krog, Dorothea, Nowotny, Peter J., Herder, Christian, Carstensen, Maren, Yoshimura, Toru, Szendroedi, Julia, Phielix, Esther, Schadewaldt, Peter, Schloot, Nanette C., Shulman, Gerald I., Roden, Michael
格式: Artigo
語言:Inglês
出版: American Diabetes Association 2013
主題:
Original Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712035/
https://ncbi.nlm.nih.gov/pubmed/23454694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-1179
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