Molecular topography of the MED12-deleted region in smooth muscle tumors: a possible link between non-B DNA structures and hypermutability

BACKGROUND: Deletions of the gene encoding mediator subcomplex 12 (MED12) in human smooth muscle tumors rank among the most frequent genomic alterations in human tumors at all. In a minority of these cases, small deletions are found. In an attempt to delineate key features of the deletions aimed at...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Markowski, Dominique Nadine, Nimzyk, Rolf, Belge, Gazanfer, Löning, Thomas, Helmke, Burkhard Maria, Bullerdiek, Jörn
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2013
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712005/
https://ncbi.nlm.nih.gov/pubmed/23738817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8166-6-23
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