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Downregulation of RhoGDIα increased migration and invasion of ER(+) MCF7 and ER(−) MDA-MB-231 breast cancer cells
Rho GDP dissociation inhibitors (RhoGDIs) can inhibit cell motility, invasion, and metastasis in cancer by inactivating the RhoGTPases. A member of RhoGDI family has been consistently shown to interact with estrogen receptor (ER), and change its transcriptional activity. ER is a receptor known to be...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Landes Bioscience
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3711997/ https://ncbi.nlm.nih.gov/pubmed/23563506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cam.24204 |
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