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Clinical significance of B7-H4 expression in matched non-small cell lung cancer brain metastases and primary tumors

BACKGROUND: B7-H4, a member of the inhibitory B7 family, is shown to have a profound inhibitory effect on the proliferation, activation, cytokine secretion, and development of cytotoxicity of T cells and may be involved in immune evasion in cancer patients. Although B7-H4 expression has been detecte...

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Autors principals: Li, Zhen-ye, Zhang, Xiang-heng, Chen, Yu, Guo, Jian-gui, Sai, Ke, Yang, Qun-ying, Chen, Zhong-ping, Mou, Yong-gao
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711949/
https://ncbi.nlm.nih.gov/pubmed/23874109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S48085
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