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Inactivation of S-adenosylhomocysteine hydrolase during adenine arabinoside therapy.
To assess for possible inhibition of cellular transmethylation during adenine arabinoside (ara-A) therapy, S-adenosylhomocysteine hydrolase activity was analyzed in 10 patients with chronic hepatitis B virus infection. In six patients receiving ara-A, enzyme activity was suppressed to 0-2% of contro...
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| Publié dans: | J Clin Invest |
|---|---|
| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Clinical Investigation
1982
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371186/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7054240/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110434 |
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