Inactivation of S-adenosylhomocysteine hydrolase during adenine arabinoside therapy.

To assess for possible inhibition of cellular transmethylation during adenine arabinoside (ara-A) therapy, S-adenosylhomocysteine hydrolase activity was analyzed in 10 patients with chronic hepatitis B virus infection. In six patients receiving ara-A, enzyme activity was suppressed to 0-2% of contro...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Sacks, S L, Merigan, T C, Kaminska, J, Fox, I H
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1982
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371186/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7054240/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110434
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