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CD8+ Effector T Cells at the Fetal–Maternal Interface, Balancing Fetal Tolerance and Antiviral Immunity

During pregnancy CD8+ effector T cells need optimal immune regulation to prevent a detrimental response to allogeneic fetal cells while providing immune protection to infections. A significant proportion of (prospective) mothers carry naïve or memory CD8+ T cells with a TCR that can directly bind to...

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Autori principali: Tilburgs, Tamara, Strominger, Jack L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711858/
https://ncbi.nlm.nih.gov/pubmed/23432707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/aji.12094
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