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Kinetic Measurements on Single-molecule Disulfide Bond Cleavage

We use single-molecule force clamp spectroscopy (SMFCS) to explore the reactivity of tris(2-carboxyethyl)phosphine (TCEP), 1, 4-DL-dithiothreitol (DTT) and hydrosulfide anion (HS(-)) on disulfide bonds within a mechanically stretched polypeptide. The single-bond level bimolecular nucleophilic substi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Liang, Jian, Fernández, Julio M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711696/
https://ncbi.nlm.nih.gov/pubmed/21341766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja109684q
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