Mapping the Subcellular Distribution of α-Synuclein in Neurons using Genetically Encoded Probes for Correlated Light and Electron Microscopy: Implications for Parkinson's Disease Pathogenesis

Modifications to the gene encoding human α-synuclein have been linked to the development of Parkinson's disease. The highly conserved structure of α-synuclein suggests a functional interaction with membranes, and several lines of evidence point to a role in vesicle-related processes within nerv...

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Huvudupphovsmän: Boassa, Daniela, Berlanga, Monica L., Yang, Mary Ann, Terada, Masako, Hu, Junru, Bushong, Eric A., Hwang, Minju, Masliah, Eliezer, George, Julia M., Ellisman, Mark H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Society for Neuroscience 2013
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711410/
https://ncbi.nlm.nih.gov/pubmed/23392688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2898-12.2013
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