Lanean...
Isolation of α(L) I domain mutants mediating firm cell adhesion using a novel flow-based sorting method
The inserted (I) domain of α(L)β(2) integrin (LFA-1) contains the entire binding site of the molecule. It mediates both rolling and firm adhesion of leukocytes at sites of inflammation depending on the activation state of the integrin. The affinity change of the entire integrin can be mimicked by th...
Gorde:
Egile Nagusiak: | , , , , , |
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Formatua: | Artigo |
Hizkuntza: | Inglês |
Argitaratua: |
Oxford University Press
2013
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Gaiak: | |
Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3711393/ https://ncbi.nlm.nih.gov/pubmed/23788664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzt028 |
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