Collagen-binding Microbial Surface Components Recognizing Adhesive Matrix Molecule (MSCRAMM) of Gram-positive Bacteria Inhibit Complement Activation via the Classical Pathway

Members of a family of collagen-binding microbial surface components recognizing adhesive matrix molecules (MSCRAMMs) from Gram-positive bacteria are established virulence factors in several infectious diseases models. Here, we report that these adhesins also can bind C1q and act as inhibitors of th...

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Detalhes bibliográficos
Main Authors: Kang, Mingsong, Ko, Ya-Ping, Liang, Xiaowen, Ross, Caná L., Liu, Qing, Murray, Barbara E., Höök, Magnus
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711317/
https://ncbi.nlm.nih.gov/pubmed/23720782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.454462
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