Rescue of Infralimbic mGluR(2) Deficit Restores Control Over Drug-Seeking Behavior in Alcohol Dependence

A key deficit in alcohol dependence is disrupted prefrontal function leading to excessive alcohol seeking, but the molecular events underlying the emergence of addictive responses remain unknown. Here we show by convergent transcriptome analysis that the pyramidal neurons of the infralimbic cortex a...

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Autors principals: Meinhardt, Marcus W., Hansson, Anita C., Perreau-Lenz, Stephanie, Bauder-Wenz, Christina, Stählin, Oliver, Heilig, Markus, Harper, Clive, Drescher, Karla U., Spanagel, Rainer, Sommer, Wolfgang H.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2013
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711176/
https://ncbi.nlm.nih.gov/pubmed/23407939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4062-12.2013
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