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Functional Analysis of the Mad1-mSin3A Repressor-Corepressor Interaction Reveals Determinants of Specificity, Affinity, and Transcriptional Response

The recruitment of corepressors by DNA-bound repressors is likely to be a critical rate-limiting step in the transcriptional regulation of many genes. An excellent paradigm for such an interaction is the association of the basic helix-loop-helix zipper protein Mad1 with the corepressor mSin3A. When...

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Publicat a:Mol Cell Biol
Autors principals: Cowley, Shaun M., Kang, Richard S., Frangioni, John V., Yada, Jason J., DeGrand, Alec M., Radhakrishnan, Ishwar, Eisenman, Robert N.
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2004
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371107/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15024060/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.7.2698-2709.2004
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