Hypoxia Induces Mesenchymal Gene Expression in Renal Tubular Epithelial Cells: An in vitro Model of Kidney Transplant Fibrosis

BACKGROUND: The development of interstitial fibrosis and tubular atrophy is a common complication after kidney transplantation and is associated with reduced long-term outcome. The hallmark of tubulointerstitial fibrosis is an increase in extracellular matrix resulting from exaggerated activation of...

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Main Authors: Zell, Stephanie, Schmitt, Roland, Witting, Sandra, Kreipe, Hans H., Hussein, Kais, Becker, Jan U.
Format: Artigo
Jezik:Inglês
Izdano: S. Karger AG 2013
Teme:
Original Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711002/
https://ncbi.nlm.nih.gov/pubmed/23898346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000351046
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