Amphetamine actions at the serotonin transporter rely on the availability of phosphatidylinositol-4,5-bisphosphate

Nerve functions require phosphatidylinositol-4,5-bisphosphate (PIP(2)) that binds to ion channels, thereby controlling their gating. Channel properties are also attributed to serotonin transporters (SERTs); however, SERT regulation by PIP(2) has not been reported. SERTs control neurotransmission by...

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Bibliographische Detailangaben
Hauptverfasser: Buchmayer, Florian, Schicker, Klaus, Steinkellner, Thomas, Geier, Petra, Stübiger, Gerald, Hamilton, Peter J., Jurik, Andreas, Stockner, Thomas, Yang, Jae-Won, Montgomery, Therese, Holy, Marion, Hofmaier, Tina, Kudlacek, Oliver, Matthies, Heinrich J. G., Ecker, Gerhard F., Bochkov, Valery, Galli, Aurelio, Boehm, Stefan, Sitte, Harald H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2013
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3710838/
https://ncbi.nlm.nih.gov/pubmed/23798435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1220552110
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