Crystal structure of Ca(2+)/H(+) antiporter protein YfkE reveals the mechanisms of Ca(2+) efflux and its pH regulation

Ca(2+) efflux by Ca(2+) cation antiporter (CaCA) proteins is important for maintenance of Ca(2+) homeostasis across the cell membrane. Recently, the monomeric structure of the prokaryotic Na(+)/Ca(2+) exchanger (NCX) antiporter NCX_Mj protein from Methanococcus jannaschii shows an outward-facing con...

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Bibliographic Details
Main Authors: Wu, Mousheng, Tong, Shuilong, Waltersperger, Sandro, Diederichs, Kay, Wang, Meitian, Zheng, Lei
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2013
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3710832/
https://ncbi.nlm.nih.gov/pubmed/23798403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1302515110
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