Alternative Approaches for Efficient Inhibition of Hepatitis C Virus RNA Replication by Small Interfering RNAs

Persistent infection with hepatitis C virus (HCV) is a leading cause of chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma. It has recently been shown that HCV RNA replication is susceptible to small interfering RNAs (siRNAs), but the antiviral activity of siRNAs depends very much on t...

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Autors principals: Krönke, Jan, Kittler, Ralf, Buchholz, Frank, Windisch, Marc P., Pietschmann, Thomas, Bartenschlager, Ralf, Frese, Michael
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
Matèries:
Gene Therapy
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC371081/
https://ncbi.nlm.nih.gov/pubmed/15016866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.7.3436-3446.2004
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