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Nucleostemin deletion reveals an essential mechanism that maintains the genomic stability of stem and progenitor cells
Stem and progenitor cells maintain a robust DNA replication program during the tissue expansion phase of embryogenesis. The unique mechanism that protects them from the increased risk of replication-induced DNA damage, and hence permits self-renewal, remains unclear. To determine whether the genome...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3710807/ https://ncbi.nlm.nih.gov/pubmed/23798389 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1301672110 |
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