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Degradation of Damaged Proteins - The Main Function of the 20S Proteasome

Cellular proteins are exposed to oxidative modification and other forms of damage through oxidative stress, disease and as a consequence of aging. This oxidative damage results in loss and or modification of protein function, which in turn compromises cell function and may even cause cell death. The...

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Detalhes bibliográficos
Main Authors: Pickering, Andrew. M., Davies, Kelvin. J. A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3710712/
https://ncbi.nlm.nih.gov/pubmed/22727423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-397863-9.00006-7
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