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Transport of the Synthetic Opioid Peptide DADLE ([D-Ala(2), D-Leu(5)]-Enkephalin) in Neuronal Cells

The Na(+)-coupled oligopeptide transporters SOPT1 and SOPT2 transport peptides consisting of ≥5 amino acids and show potential for the delivery of therapeutically relevant peptides/peptidomimetics. Here we examined the expression of these two transporters in the retinal neuronal cell line RGC-5. The...

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Autori principali: ANANTH, SUDHA, THAKKAR, SANTOSHANAND V., GNANA-PRAKASAM, JAYA P., MARTIN, PAMELA M., GANAPATHY, PREETHI S., SMITH, SYLVIA B., GANAPATHY, VADIVEL
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3710446/
https://ncbi.nlm.nih.gov/pubmed/21905028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.22733
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