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Voltage-gated sodium channels: Pharmaceutical targets via anticonvulsants to treat epileptic syndromes
Epilepsy is a brain disorder characterized by seizures and convulsions. The basis of epilepsy is an increase in neuronal excitability that, in some cases, may be caused by functional defects in neuronal voltage gated sodium channels, Nav1.1 and Nav1.2. The effects of antiepileptic drugs (AEDs) as ef...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3710341/ https://ncbi.nlm.nih.gov/pubmed/23531742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.24380 |
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