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Voltage-gated sodium channels: Pharmaceutical targets via anticonvulsants to treat epileptic syndromes

Epilepsy is a brain disorder characterized by seizures and convulsions. The basis of epilepsy is an increase in neuronal excitability that, in some cases, may be caused by functional defects in neuronal voltage gated sodium channels, Nav1.1 and Nav1.2. The effects of antiepileptic drugs (AEDs) as ef...

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Главные авторы: Abdelsayed, Mena, Sokolov, Stanislav
Формат: Artigo
Язык:Inglês
Опубликовано: Landes Bioscience 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3710341/
https://ncbi.nlm.nih.gov/pubmed/23531742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.24380
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