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Why should we care about fly tumors?: The case of JAK-STAT and EGFR cooperation in oncogenesis

Drosophila is proving to be a valuable model for studying aggressive tumors induced by the combined activation of EGFR and JAK-STAT signaling. Here we summarize some of the most recent data showing that tissue damage and the modulation of common pathway regulators are at the heart tumor progression...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hombría, James Castelli-Gair, Serras, Florenci
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3710316/
https://ncbi.nlm.nih.gov/pubmed/24058803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/jkst.23203
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