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Dissociation of systemic and renal effects in endotoxemia. Prostaglandin inhibition uncovers an important role of renal nerves.

To elucidate the mechanisms responsible for systemic and renal hemodynamic changes in early endotoxemia, the roles of prostaglandins (PG) and renal nerves were investigated. Endotoxin (E, 3 micrograms/kg i.v.) was given to two groups of anesthetized dogs that had undergone unilateral renal denervati...

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Vydáno v:J Clin Invest
Hlavní autoři: Henrich, W L, Hamasaki, Y, Said, S I, Campbell, W B, Cronin, R E
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 1982
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371027/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7037854/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110497
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